George Holmes (fl.1789–1804) was a pupil in the Dublin Society's School, where he won a medal for landscape drawing in 1789. Afterwards he found employment making drawings of views for book illustrations. Engravings after his work appeared in a number of books and magazines throughout the 1790s. His subjects were Irish, often including castles and priories, such as Roebuck Castle, Dunloe Castle, Blarney Castle and Swords Castle, and St John's Priory, Kilkenny and Cashel Cathedral.

In the autumn of 1797 he toured southern Ireland, and the resulting pictures were published in London in 1801 in a book entitled 'Sketches of some of the Southern Counties of Ireland collected during a Tour in the autumn of 1797, in a series of Letters'. Six views after Holmes were engraved in aquatint by Samuel Alken, including the Rock of Cashel, Cormac's Chapel, Interior of the Abbey of Holycross, Ross Castle, Muckross Lake and Castle of Lismore.

It is thought that Holmes left Ireland around 1799, exhibiting at the Royal Academy between 1799 and 1802. Five drawings by Holmes are in the British Museum collection.